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Red blood cells parameters of maternal and umbilical cord 


Gastroenterology & Hepatology: Open Access
Nassreldeen Khalid Abdelraman Adam,1 Maisa Abaker Mohammed Abdoalhadi,2 Nahla Ahmed Mohammed Abderahman,3 Mohammed Ahmed Ibrahim Ahmed4

Abstract

Background:It is debatable if the mother's iron level affects the fetal red blood cell parameters and whether the fetus' blood develops independently of the mother. When diagnosing and monitoring newborn anemia, the values of hemoglobin (Hb) and hematocrits (HCT) were involved. Neonatal hematological illness is typically diagnosed using samples of umbilical cord blood.

Objective: The objective of this research was to determine whether or not there is a relationship between maternal and cord blood red cell parameters.

Methods:At the Al-Fashir Maternal Hospital in North Darfur, Sudan, a cross-sectional study was carried out, including 100 mothers who were giving birth between January and March 2015. In an EDTA-containing tube, three milliliters of venous blood were drawn to measure the mothers' red blood cell parameters prior to birth. Immediately upon delivery, the babies' umbilical cords were clamped and the babies' end of the cord was cut in order to collect five milliliters of cord blood. Hematological parameters were measured using a conventional coulter gram, comprising measurements of hemoglobin (Hb), RBC count, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration.

Results: 100 samples of umbilical cord blood and 100 samples of maternal blood were combined for the analysis. All of the red blood cell characteristics, with the exception of MCHC, were discovered to be higher in the cord blood samples than the maternal blood samples. Statistics showed that the difference was significant. While 59 (59%) of the moms had normal red blood cell characteristics, 41 (41%) of the mothers were anemic. There were no statistically significant differences between newborns with anemic mothers and those with normal mothers when red blood cell parameters were compared. Red cell indices for mothers and neonates did not correlate statistically significantly, including Hb (r=0.13, P-value: 0.2), HCT (r=0.1, P-value: 0.24), RBCs (r= 0.1, P-value: 0.29), MCV (r=0.06, P-value: 0.54), MCH (r= 0.07, P-value: 0.48), MCHC (r= 0.09, P-value: 0.36), RDW-SD (r=0.09, P-value: 0.32) and RDW-CV (r=0.08, P-value: 0.46). There was no significant variance between the red blood cell parameters of male neonates (46%) and female neonates (54%) as well as the link between the red blood cell parameters of cord blood and mothers' ages.

Conclusion:Maternal and cord blood red cell parameters did not significantly correlate. In comparison to maternal blood samples, all of the red blood cell characteristics were shown to be higher in cord blood samples except for MCHC.

Keywords

CBC, complete blood count, RBCs, red blood cells count, Hb, hemoglobin, HCT, hematocrit, MCV, mean corpuscular volume, MCH, mean corpuscular hemoglobin, MCHC, Mean corpuscular hemoglobin concentration, RDW-SD, red cell distribution width-standard deviation, PCV, packed-cell volume, RDW-CV, red cell distribution width -coefficient of variation

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