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Water - a foundation of dissipative regulation of a living organism

MOJ Biology and Medicine
Igor Orzhelskyi,1 Andrey Kuznetsov2


Dissipative processes of self-organization occur in both living and non-living matter. The same laws govern living and non-living matter, but the mechanism of their manifestation is different. The distinctive feature of living matter is “functional information,” which is an attribute characteristic only of living matter. Functional information is a purposeful indication of the change in the structural-functional state of the living matter. Feedback plays an essential role in self-organization and the dynamic balance of dissipative systems. Self-organization is based on positive feedback (PF). Dynamic equilibrium of the system is ensured by negative feedback (NF). There is a constant competitiveness between the two types of feedback - PF and NF. In biological systems, the balance of PF and NF is maintained based on auto-oscillatory homeostasis processes. The regulatory function of homeostasis correlates with the dynamics of the ratio of free and bound water phases in the hydration-dehydration processes of biopolymers. Water regulates homeostasis and supports metabolism by maintaining the bound-free water phase ratio balance.


dissipative systems, dissipative self-organization, dissipative regulation, entropy, functional information, system sensitivity, self-oscillations, feedback, homeostasis, bound and free water, hydration, dehydration, biopolymer conformation, information density, synchronization, desynchronization