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Primary neurendocrine tumor of the liver, an exceptional location

Gastroenterology & Hepatology: Open Access
Ouaya H,1 Benjouad K,1Aiterrami A,1 Oubaha S,2 Samlani Z,1 Bouyali C,3 elhadri K,3 Boutakioute B,3 Ouali Idrissi M,3 Cherif guenoun El Idrissi N,3 Krati K1

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The digestive endocrine tumors have mainly gastrointestinal and duodenopancreatic localization. Liver metastases are frequent there. The primary hepatic localization remains exceptional. We report a new observation revealed in a 42-year-old man with an abdominal pain and deterioration in general condition. The CT scan and histologic appearance of the percutaneous biopsy were in favor of hepatocellular carcinoma. The immunohistochemical study showed the endocrine nature of the tumor. The various endoscopic and morphological examinations, in particular the octreoscan, eliminated any extra-hepatic localization, which made it possible to retain the primary hepatic origin of the tumor.


endocrine tumor, liver, immunohistochemistry, octreoscan, CgA, chromogranin A, 5HIAA, 5-hydroxyindole acetic acid, NETs, Neuroendocrine tumors