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An active transport refrigerator is optimal for blood preservation in small medical facilities

Hematology & Transfusion International Journal
Hiroshi Fujita,1 Katsuhiro Tsuno,2 Asashi Tanaka3

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  1. Objective:In small medical institutions in Japan, red blood cell (RBC) solutions are commonly stored in household refrigerators because of the high cost of blood-only refrigerators. Therefore, we assessed and compared the methods used for preserving the RBC solutions in an active transport refrigerator (ATR), a blood-only refrigerator, and a household refrigerator.
  2. Materials and Methods:Irradiated RBC solution samples (280 mL) supplied by the Japanese Red Cross Society (experiments 1–8) and in-house whole blood waste (experiments 9–10) were each divided into two bags. The quality of blood stored in an active transport refrigerator was compared with that of blood stored in a blood-only refrigerator or a household refrigerator. We tested the hemolytic effects of storage and filtration through a transfusion set on the lactate dehydrogenase ratio (LDR) of the RBC solutions.
  3. Results:Although the LDR of the RBC solutions stored in the ATR was similar to that of the RBC solutions stored in the blood-only refrigerator, the LDR of the RBC solutions stored in the household refrigerator was significantly higher than that of the RBC solutions stored in the ATR.
  4. Conclusion:Temperature management using an ATR is critical for the maintenance of the quality of the RBC solution, which is not achieved by a household refrigerator.


home transfusion, red blood cell solution, hemolysis