Hyper IgE Syndrome, emphasis on radiological findings: A case of pulmonary complications in a pediatric patient
- Journal of Pediatrics & Neonatal Care
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Jennifer Richardson Maturana,1 Nathalia Jacome Perez,2 Luz Ángela Moreno Gómez,3 Rubén Danilo Montoya Cárdenas,3 Lina Maria Castaño Jaramillo,4 Carlos Enrique Camargo Crespo5
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Abstract
Background: STAT3 hyper IgE Syndrome (STAT3-HIES), is a rare immunodeficiency that affects multiple organ systems. A clinical triad characterizes it and includes recurrent skin abscesses, frequent respiratory tract infections, and elevated levels of immunoglobulin E in the blood.
Case report: A 9-year-old female patient with STAT3-HIES was brought to the emergency
department for cold abscesses. During her assessment, the patient was diagnosed with a
large pneumatocele and cystic lung lesions detected by a CT scan. The patient underwent a
successful surgical intervention, without complications.
Conclusions: This case underscores the importance of performing a complete and prompt
evaluation along with multidisciplinary management in STAT3-HIES patients to prevent
potentially life-threatening complications.
Keywords
hyper-IgE syndrome, job syndrome, signal transducer and activator of transcription 3 (STAT3)
