Abstract

Introduction: Atopic dermatitis is a common, relapsing chronic inflammatory skin condition. Pruritus is a frequent complaint of patients with atopic dermatitis which can impair quality of life. The aim of this study is to evaluate the use of Kānuka Oil 3% cream as a treatment option for this diseased population. Methods: A randomized, double-blinded study was performed with 40 patients split into two treatment groups with the application of either kānuka oil 3% cream or hydrocortisone 1% cream. ISGA and WI-NRS assessments were performed at baseline, week 2, and Day 28. Results: Kānuka Oil 3% cream showed statistically significant improvement in ISGA scores compared to hydrocortisone 1% cream (p=0.0082) at day 28. Worst Itch Numerical Rating Scale (WI-NRS) scores exhibited kanuka oil 3% cream showing greater improvement in itch reduction compared to hydrocortisone 1% cream by day 6. No adverse effects were reported by patients in either arm of the study. Conclusion: Kānuka oil 3% cream offers a novel therapeutic option for patients with mild atopic dermatitis. The improvement in itch has the potential to improve the quality of life of patients inflicted with atopic dermatitis.

Keywords

atopic dermatitis, kanuka oil 3% cream, pruritus, hydrocortisone cream