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Influence of inter-and inter-pair distance of electrode arrays on tumor treatment


Physics & Astronomy International Journal
Leonardo Mesa Torres,<sup>1</sup> Ivelice Gonzales Delgado,<sup>2</sup> Enaide Maine Calzado,<sup>3</sup> Jorge Luis García Rodríguez,<sup>4</sup> Luis Enrique Bergues Cabrales<sup>5</sup>

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Abstract

Electrochemical therapy (EChT) is used for the treatment of cancer. The application of this therapy is simple, safe, effective and induces minimal adverse events in the organism. The objective is to evaluate the induced effectiveness of the distance of the electrode arrays (single and multiple pairs) for the quantification of the percentage of tumor destruction (PDT). A computer program was used for the calculation and simulation of PDT and a sample of (24 male and 24 female) BALB/c/Cenp laboratory mice. It is concluded that this therapy is effective for the treatment of tumors since the percentage of tissue damage increases; by more than 80% at a distance (0.5 ≤ d ≤ 1) cm from the electrode arrays inserted perpendicularly in the tumor geometry, which allows its use for the treatment of different types of tumors.

Keywords

tumor treatment, electric field, electrode arrays, electric field, tissue damage

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