Abstract

In recent years, platelet-rich plasma (PRP) rich in growth factors (PRGF) has emerged as a promising autologous biological therapy alternative for use in cosmetic and regenerative medicine. PRGF is a high concentration of platelets extracted from whole blood, and platelet-containing plasma is separated and concentrated from red blood cells by centrifugation. The hundreds of bioactive proteins that make up PRGF, including cytokines, peptides, and growth factors, aid in the healing of skin and soft tissues. PRGF has several attractive features, including tissue regeneration and healing capabilities, the extended release of several growth and differentiation factors from activated platelets, and the lack of immunogenicity problems. Because of its unique biological properties, PRGF has a wide range of clinical uses in regenerative and cosmetic medicine. This paper’s main objective is to highlight a fantastic, effective method for treating osteoarthritis (OA) in the knee (KOA). It also highlights the significant influence that our exceptional M.Sc. thesis has had. 

Keywords

Egypt, knee osteoarthritis (KOA), MSc thesis, PRP, PRGF