Abstract

Aging is a multidetermined collective process reflecting desynchronization of molecular interactions with persistent disintegration of Proteostasis. Hormonal imbalance, DNA damage, elevated toxicity and inflammation are central to the body’s eventual disharmony as time goes by. Impairment of autophagy and mitochondrial function, reduced stem cells’ differentiation, and interruption of cellular trafficking or distortion of exosome signals accumulate to disentangle cellular communications, inevitably triggering physical dysfunction. Most aging theories are either inconclusive, incongruous with each other, or demonstrate a narrowed focus on one piece of the biological mosaic of entangled life processes. Optimistic advocates of stem cells and exosomes are blindfolded dismissing the risk and deleterious effects of systemic incompatibility that ranges from low to severe, depending on manufacturing variability and individual differences. Then, there is the issue of marketing shadowing science and restricting the public’s visibility down to a limited selection of trauma-based procedures. A simple blood test comparing the young with the old will render aging synonymous with low-grade inflammation, hormonal imbalance, increased lipids and glucose, insulin resistance, visceral adipose tissue deposits, fatty liver and/or compromised function of more than one vital organ. Aging defects usually persist despite lifestyle changes and regular exercise. None of these systemic deficits can be reversed by trauma-based energy devices which have no evidence to definitively claim body synchronisation or rebalancing. Traumabased procedures have not provided longitudinal studies proving wellness or results that do not rebound due to persistent metabolic issues and/or unsuppressed hunger. So how can these currently popular technologies claim that they offer a solution to the antiaging puzzle? Inner biological disharmony undermines immunity and breeds several diseases affecting both the human healthspan and lifespan. Instead of identifying isolated aspects of biological processes or studying different diseases separately, we can encompass a more comprehensive perspective of molecular interactions that visualize health and antiaging as an entangled multifactorial whole that requires equilibrium and harmonization to function optimally. This article examines different angles of antiaging research and mentions some underreported technologies that can synchronize the body to empower health and delay aging.

Keywords

Aging, DNA damage, exosomes, stem cells, genomic stress, epigenetic damage, stem cells, gene expression, proteostasis, hormonal balance, effortless exercise, resonance energy transfer, inflammation, radical damage