Objective: HA, due to its high reversibility, low incidence of adverse events, and patient acceptance, is a viable option for correcting mild to severe retrognathia. This work aims to systematize and suggest non-surgical options that impact profilometry through the ProT technique.

Methods: Depending on the level of retrognathia, HA injections are administered in varying depths, with severe cases also requiring neuromodulator treatment. Proper injection techniques and materials are recommended to enhance treatment effectiveness and durability. 

Results: The case series showed significant improvements in mental region projection and definition, with 40%, 50%, and 70% enhancements for cases 1, 2, and 3, respectively. Case 2 also had a 15% increase in the distance from the oral commissure to the mandibular base and a 3.25 cc volumetric gain in the mental region. These results indicate substantial improvements in facial aesthetics following the intervention. 

Limitations: We can consider individual anatomical variations, organism response, and the professional’s application technique as limiting factors for technique reproducibility. 

Conclusion: The Profile Technique (ProT) utilizes hyaluronic acid (HA) gels and, optionally, neuromodulators tailored to each patient’s facial profile to correct retrognathia effectively. This approach results in significant improvements in facial aesthetics while ensuring safety, making ProT a minimally invasive and effective method for enhancing facial harmony.