Home Magazines Editors-in-Chief FAQs Contact Us

Pancreatic rest in a young woman: a rare cause of dyspepsia


Ectopic pancreatic tissue or heterotopic pancreatic tissue, also known as a pancreatic rest, is an uncommon congenital anomaly defined as displacement of small amount of pancreas during embryonic development, resulting in the formation of a nodule located far from the pancreas and without any connection via vascular or anatomical means. It can be seen in any part of the gastrointestinal tract with larger percentages found in stomach followed by small intestine especially in duodenum and jejunum. It may remain silent over period of years or present clinically mimicking symptoms of acid peptic disease, ulcer, upper gastrointestinal tract bleeding and obstruction. Infrequently, it may lead to pancreatitis or pancreatic cancer. Radiological appearances are variable ranging from small lesion to large masses. Histopathological diagnosis remains the gold standard. This report describes the clinical scenario of severe dyspeptic symptoms of twelve weeks duration in a young female. She underwent upper gastroscopic examination, which revealed a nodular lesion in the antral portion of the stomach. After resection of nodule and proton pump inhibitors of 1-month duration her symptoms improved. The histological specimen revealed the presence of pancreatic rest and no evidence of malignancy was noted. The patient is symptom-free and has been followed up in our clinic.


heterotropic pancreatic tissue, acid peptic disease, pancreatic rest, pancreatitis, theory of metaplasia, gastrointestinal bleeding, gastrointestinal tumor