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Lasers & topical vitamin C: scars in ehlers-danlos

Journal of Dermatology & Cosmetology
Gabriella Alvarez,1 Nathan Leisenring,2 Martin Nunez,2 Amanda Suggs2

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Background: Hypermobile Ehlers-Danlos Syndrome (hEDS) is a connective tissue disorder with cutaneous manifestations including poor wound healing and atrophic scar formation. There is evidence supporting the use of topical vitamin C and laser for scar revisions, but limited reports of using topical vitamin C in scar revisions in patients with
Objective: To present a case where topical vitamin C applied post-laser treatment resulted in improved healing and aesthetic outcomes in a patient with a connective tissue disorder.
Methods: We present a case of treatment of atrophic and hypertrophic scars in a patient with hEDS with ablative fractional laser, pulsed dye laser, and post-procedural topical vitamin C. We discuss the patient’s treatments, outcomes, and previous literature on the matter.
Results: This patient had markedly improved wound healing after topical application of vitamin C post-laser treatment with no complications. Additionally, the patient had improved aesthetic outcomes with topical vitamin C and laser treatment just after one session.
Conclusion: This case suggests that hEDS scars may be safely treated with lasers when combined with post-procedural topical vitamin C.


ehlers-danlos, ablative laser, vitamin c, wound healing, scars