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Morphine - bupivacaine and bupivacaine in gynecological surgeries

MOJ Surgery
Mirelys Valladares Díaz,Taimilquis León Perón,2 Annelis Pérez Rodríguez3

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  1. Objective: Evaluate the intrathecal use of morphine-bupivacaine and bupivacaine in gynecological surgeries.
  2. Material and methods: An analytic longitudinal prospective study was perfomed at the Manuel Piti Fajardo Hospital in Florida, from February 2019 to March 2020. The universe was compound by 180 patients. Sample was select about 60 patients by probabilistic simple randon sampling distributed in two groups: A (Morphine -Bupivacaine) and B (Bupivacaine) according to inclusion criteria. The data were collected in questionnaire properly to investigation with baseline data in Statistical Package for Social Sciences. A univariate and multivariate analysis were conducted.
  3. Results:Complications and adverse reactions and their probability of presentation in the morphine=bupivacaine group was greater, pruritus (3.5 times), nausea and vomiting (2.8 times), hypotension (2.1 times) and urinary retention (2.1 times) corroborated by confidence intervals.This group had ten times more probability to have tolerable trouble or no pain (QR=10,2) that bupivacaine group, all of which showed moderate to several pain;10 times more probability of analgesia greater to 24 hours (QR=10,7) compared to bupivacaine and 8 times more likely to perceive good satisfaction.
  4. Conclusions:Evaluation of pain postoperative and analgesic time were better in patients managed with morphine =bupivacaine that resulted in analgesic of the greatest quality although prevailed pruritus, nausea and vomiting, hypotension and urinary retention like adverse reactions.


postoperative pain, analgesia, satisfaction, adverse reactions