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Analysis of decontamination of pressure injury through blue light - randomized trial clinical study

Biometrics & Biostatistics International Journal
Alessandra Bongiovani Lima Rocha, Renato Araujo Prates, Priscila Angélica Seiko Sato, Rodrigo Labat Marcos, Paulo de Tarso Camillo de Carvalho, Luciana Soares Costa Santos, Acácia Maria Lima Oliveira Devezas, Júlia Teixeira Nicolosi, Carla Maria Maluf Ferrari


Objective: to analyze the effects of photobiomodulation using the Light-emitting Diode (LED), operating at wavelength 420 +/- 20 nm (Violet-Blue) in pressure decontamination (PI). Methods: The sample consisted of 36 patients, 24 of whom met the inclusion criteria and were randomized into 3 treatment groups, where three different photobiomodulation We used a Cosmedical® LED plate Cicatrillux (figure 1); containing 36 LEDs, 420 +/- 20 nm, optical diameter 10 mm +/- 2, optical output 2-5 mW, device energy 106J, radiant exposure 3.8 J / cm2, irradiance 6.4 mW / cm2 whit energy total Joules were applied in each, 53J (5 min) 106J (10 min) and 159J (15 min) respectively. Results: The analysis of the results was based on the counting of Colony Forming Units (UFC), as well as characterization of the lesions using the National Pressure Ulcer Advisory Panel (NPUAP) and severity by the Pressure Ulcer Score Healing (PUSH) scale. The mean age of the study patients was 72 years, most of the pressure lesions were in the sacral region (70%), 62% female patients, 79% of the lesions were located in the sacral region and 54% were stage III. Conclusion: The analysis of the results showed that the photobiomodulation of lesions at wavelengths of 420 nm to reduce contamination was not effective at the doses applied in the three study groups because, despite a slight reduction in CFU count in the time of 159J, was statistically significant.


photo biomodulation, bacterial inactivation, pressure injury, bacterial infection, blue light