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Posterior reversible encephalopathy syndrome in a patient with mixed connective tissue disorder: a case report

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Our case report includes a 42-year-old female patient; a known case of Mixed Connective
Disorder (MCTD) who presented with focal seizure. Magnetic Resonance Imaging (MRI)
brain showed the features of Posterior Reversible Encephalopathy syndrome (PRES) to be
the cause of seizure. Given the timely diagnosis of PRES, the seizure was controlled with
anti-epileptic drug and the possibility of having poor neurological outcome was successfully
prevented. Although Mixed Connective Tissue Disorder is rarely associated with PRES,
MCTD should be considered when there are supportive clinical and radiological findings
as in our case.


Posterior Reversible Encephalopathy syndrome, Mixed Connective Tissue Disorder, Hydroxychloroquine.