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Mirizzi syndrome: case series and literature review

MOJ Anatomy & Physiology
Julio Ángel Barajas Puga,1 Elia Aìda Lira Alvarez,2 Esteban Zacarias Leaños,3 Francisco Rico Fernández,3 Luis Jorge Caldera Sánchez,3 Salvador Guillermo Cabrera Medina1

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Introduction: Mirizzi syndrome (MS) is defined as extrinsic obstruction of the main bile
duct by a stone impacted in the cystic duct or in the infundibulum of the gallbladder.
Objective: To determine the incidence and describe the management of 15 cases diagnosed
in the General Hospital of Zacatecas “Luz González Cosió”.
Material and methods: Retrospective, observational, cross-sectional and comparative
study, age, sex, diagnostic method, surgical management are described.
Results: 719 cholecystectomies were performed in a period of 3 years, 15 cases of MS were
found, with an incidence of 2.07%, the diagnosis was made intraoperatively in 11 cases, 10
cases (66%) were type I, 3 cases (19.8%) type V, 1 case (6.6%) type III and 1 case (6.6%)
type IV, for type I 10 cholecystectomies were performed, the other types had a specific
surgical management.
Conclusion: It is a complex pathology of difficult pre-surgical diagnosis. It must be treated
by experienced surgeons to reduce the risk of the dreaded bile duct injury.


Mirizzi syndrome; Cholelithiasis; Cholecystitis; Surgical management