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Evaluation of serum iron and vitamin E in Wistar rat administered with Boletus edulis extracts


Hospice & Palliative Medicine International Journal
Nnodim Johnkennedy, Njoku-Obi Treasure, Osuoha Chinyere, Ohalete Chinyere, Ikem Promise Amarachi

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Abstract

This study was carried out to determine the levels of iron and vitamin E in wistar rats administered with Boletus edulis extracts. Twenty-four adult male rats weighing between 100g and 120g were assigned into four groups of six rats each. Group A served as a healthy Control group. Group B, C and D were administered with extract of Boletus edulis with a dose concentration of (40mg/kg, 80mg/kg and 120mg/kg body weight) respectively for 28 days. The results obtained showed that administration of Boletus edulis caused a significant increase in iron and serum vitamin E when compared with the control group (P<0.05). These changes in the serum iron and serum vitamin E were dose dependent. This observation probably implies that Boletus edulis extract could probably be beneficial in the treatment of anaemia and fertility issues. 

Keywords

Boletus edulis, iron, vitamin E

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