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The vision-related quality of life and anxietydepression levels of age-related macular degeneration during COVID-19 Pandemic

Advances in Ophthalmology & Visual System
Ismail Ersan,1 Erhan Akinci,2 Burak Turgut,1 Sercan Cate1

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Purpose: To evaluate anxiety, depression status, and vision-related quality of life (QoL) in patients with age-related macular degeneration (AMD) during the early phase of the COVID-19 pandemic. Methods: Seventy-one voluntary patients with AMD and demographic variables matched 36 healthy controls were compared in this study. All the subjects were evaluated with the Hospital Anxiety and Depression Scale (HAD-A and HAD-D) and National Eye Institute Visual Functioning Questionnaire-25 (NEI-VFQ-25). Results: There was no statistically significant difference in HADS-A and HADS-D between the AMD group and controls (p<0.05) When the patients with AMD were assigned to two distinct groups according to binocular visual acuity, the proportion of patients above the HADS cut-off points for anxiety did not differ between the groups (p=0.208) and 55.6 % of patients above the HADS cut-off points of depression in low vision AMD group were significantly different from other groups (p=0,022). The statistically significant lower means of NEI-VFQ-25 parameters except for general health and ocular pain were observed in AMD patients compared with controls (p<0.05). Conclusions: Higher rates of depression were observed in subgroup of AMD having poor visual acuity. The AMD patients had lower vision-related QoL scores during the COVID-19 pandemic and it is recommended psychiatric counseling opportunities are needed for AMD patients having low binocular visual acuity.


anxiety, depression, coronavirus disease 2019, COVID-19, quality of life, macular degeneration