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Stroke in Maputo central hospital, Mozambique: a cross-sectional study 2014–18

Journal of Neurology & Stroke
Yanina Baduro,Omer Ndala,1 Deise Vaz Helena Buque,Frederico Sebastião,1 Jamal Baco,1 Nachan Arroz,1 Carlos Casas,1 Elder Lorenzo,1 Manuel Mahoche,3 Jorge AH Arroz2


Objective:Stroke is the second leading cause of death worldwide. The prevalence of hypertension (the major risk factor for stroke) in Mozambique increased from 33.1% in 2005 to 38.9% in 2014/2015, although awareness and control remained at very low levels (15% and 3%, respectively). The aim of this study is to characterize the demographic and clinical pattern of stroke in Maputo Central Hospital (MCH), Mozambique.

Methods:A cross-sectional hospital-based study was carried out in MCH, collecting secondary data from hospitalized patients with stroke. Using systematic probabilistic sampling, clinical records were used to analyze data for the period 2014-18.

Results:Of the 402 clinical records, 53.5% were female. The mean age was 60.68 years (13.98 SD). Around 96% was an acute stroke event, and 91% was first-ever episode. Thirty one percent did not receive a CT scan for confirmation. Of the 247 CT scanned patients, 50.2% were ischemic. The area of middle cerebral artery was affected in 83.4% patients. The most common co-morbidity was hypertension (87.1%). Near 96% of hemorrhagic stroke were associated with hypertension (Ischemic = 78.7%, p < 0.001). The overall case-fatality was 22.9%. Confirmed hemorrhagic stroke patients were 6.47 years younger than ischemic (56.40 vs 62.87 years; p < 0.001).Younger ages and female were associated with clinical improvement (aOR = 0.964; p = 0.002 and aOR = 1.890; p = 0.044, respectively). Hemorrhagic stroke were 56.8 percent points more likely associated with death (aOR = 0.432; p = 0.010). The likelihood of clinical improvement was 20.5 percent points better over the years (aOR = 1.205; p = 0.086)

Conclusions:Stroke associated with hypertension is common in MCH, mostly likely due to an increase in hypertension prevalence and extremely low awareness and control. Favorable clinical outcome improved over the years. Efforts for CT scan to all stroke episodes should be emphasized by MCH managers.


stroke, cross-sectional study, Maputo central hospital, Mozambique