Abstract

Type 2 diabetes mellitus (T2DM) is the most frequent metabolic disease encountered in
India. One of the most fearful complications associated with T2DM is acute coronary
syndrome (ACS). In contrast to the non-T2DM patients T2DM patients presents with
atypical clinical picture and has a worse prognosis. Electrocardiogram (ECG) is a very
important tool used to diagnose ACS. The ST-segment elevation (STEMI) pattern in ECG
is associated with a significant and prolonged occlusion of the coronary arteries. The aim of
this pilot project was to highlight the difference in ECG presentation between T2DM patients
and their non-T2DM counterparts (if any). Relevant data was collected from 29 consecutive
patients presenting with AMI in the cardiac care center in Nightingale hospital, Kolkata,
India, after procuring their informed consent. The data was analyzed using the presence
or absence of STEMI as the categorical output and its association with T2DM status as the
input. The association was assessed using chi-square statistics. Jupyter notebook was used
to perform the statistical analysis. The mean age of the selected population was 61.2 years
with a mean blood pressure (BP) of 136/77 mm of Hg. There was a significant association
between T2DM and STEMI (P=0.02), as assessed by chi-square statistics. In this small
cohort from Kolkata, T2DM was significantly associated with an ECG presentation of
STEMI in patients with AMI

Keywords

Type 2 diabetes mellitus