Home Magazines Editors-in-Chief FAQs Contact Us

Kaposi's sarcoma a series of cases and review of the literature


MOJ Clinical & Medical Case Reports
Naranjo Cruz Alondra Yeraldi,1 Hernández Hoil Lorena Berenice,2 Chávez Hernández María Margarita,3 Jiménez-Baéz María Valeria4

Abstract

Introduction: Kaposi's sarcoma is a neoplasm associated with the Human Immunodeficiency Virus (HIV) - AIDS especially in advanced stages, in Quintana Roo HIV-AIDS ranks first in the country. 
Methodology: A series of 22 cases with diagnosis confirmed by biopsy attended by the oncology service of HGR No. 17 is presented.
Results: They were classified as low risk (4); three of them with complete response. High risk(18); fifteen accepted chemotherapy. Nine (60%) received liposomal doxorubicin and six (40%) paclitaxel; of these, four had a complete response, one partial response, six with stable disease and five with disease progression that required a second line. The presence of adverse effects associated with chemotherapy treatment was documented in six patients classified as high risk (40%). 
Conclusions: Clinical interventions with therapeutic trials are necessary, since the available evidence dates from periods of more than 10 years ago. HIV patients require continuous monitoring and clinical trials to improve the therapeutic options available to treat one of the most common oncological diseases in this population such as Kaposi's Sarcoma.

Keywords

kaposi, HIV, AIDS, liposomaldoxorubicin, paclitaxel, angioproliferative tumor, chemotherapy, angioproliferative features, antiretroviral use

Testimonials