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Repercussion of palliative care on survival in patients with High-grade Glioma

Journal of Neurology & Stroke
Gloria Esther Castillo-Lara,1 Sonia Edith Hancco-Huillca,2 Gloria Esther LaraFernández,3 Gabriel Andres Peña-De los Santos,4 Gabriela Leyva-Coll, 5 Rocio Anel Loaces-Padrón6

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Aim: To determine the influence of education in early neuro-palliative care, on the survival of patients diagnoses with high-grade glioma, to evaluate the overload associated with the care of such patients. Method: was an observational, cross-sectional, descriptive, and exploratory study in 52 patients and caregivers with High-grade glioma tumors as the pathological diagnosis, treated at the Institute of Neurology and Neurosurgery of Havana from January 2019 to January 2020. Results: The care provision system was in charge of family members in 51.9% of the patients, predominantly female in this task; 45 (86.7%), 42.2% of which maintained a labor relationship, with a mean age of 53.9 years. The Zarit test was applied in the 52 caregivers, intense overload was recorded in 33 (63.5%), mild in 10 (19.2%) and no overload in 9 (17.3%). Patients in whom their caregivers received education in palliative care at the time of HGG diagnosis had 57.1 more days of survival, unlike those who received it in the period of neurological deterioration (241.7 vs 184.6 days). Survival time was influenced by the record of caregiver burden. Conclusion: The overall survival life time was directly related to the caregiver’s education in palliative care and the time it was received, early palliative care education, could influence prolonging life.


end of life, palliative care, family caregivers, high-grade glioma, malignant brain tumor