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Acute kidney injury in COVID-19: irrational use of drugs in clinical practice

Urology & Nephrology Open Access Journal
Correa- Prieto Franklin Rouselbel

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Acute kidney injury is associated with higher mortality in COVID-19 patients. The causes of acute kidney injury can be stratified into three: due to direct cytopathogenic effect, secondary damage due to the coexistence of the inflammatory response or due to the patient’s therapy. It is the last point at which you must have the best criteria to make the correct decisions, based on evidence. The administration of antibiotics in patients with COVID-19 is directly related to the critical judgment of the clinician and his experience, therefore, the prescription of antibiotics in patients with SARS-CoV-2 infection should be avoided as clinical practice of outpatient or hospital management, if the presence of a concomitant bacterial infection has not been evidenced in any way. Selective or multiple treatment of COVID-19 patients should be based on physiological knowledge and principles; as well as those of the natural history of the disease, pathophysiology and a critical analysis of the available information; but not only the experience -which is scarce in this disease-, maintaining a focus on evidence-based medicine.


COVID-19, severe acute respiratory syndrome coronavirus 2, acute kidney injury, evidence-based medicine, evidence-based emergency medicine, evidence-based practice