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Prevention of pediatric chronic kidney disease

Urology & Nephrology Open Access Journal
Rejane de Paula Bernardes,1 Nilzete Liberato Bresolin,2 Maria Goretti Moreira Guimarães Penido3

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Prevention of kidney disease must begin before a woman becomes pregnant. For this prevention, it is necessary to act with doctors, health professionals, parents, schools and the community. This early prevention is important because the pathophysiology of chronic noncommunicable diseases in adults would be related to events that occur during the prenatal period and in the first year of life. In an unfavorable intrauterine environment, the embryo/fetus undergoes adaptations resulting from epigenetics and intrinsic factors that could cause a renal maturation compromised. This is what we call fetal and perinatal programming of kidney diseases in adults. There are three types of prevention: the primary that aims to eliminate or reduce exposure to risk factors for chronic kidney disease, the secondary that eliminates or reduces exposure to risk factors and the tertiary that reduces or postpones long-term disease complications. However, the best and most effective prevention is the primary one with actions to control the future mother, the pregnant woman, the infant and older children until adolescence. The main primary prevention agents for kidney disease include the community, doctors and other health professionals, parents and caregivers, schools and day care centers. In this way, it will be possible to control the explosion of chronic kidney disease worldwide.


chronic kidney diseases, primary prevention, fetus, embryo,infants