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Affinity of liver cells to Sudanophilia and PAS in castrated treated mice


MOJ Anatomy & Physiology
Homady MH,1 Alquraishi LO,2 Ali M Hussein,3 Omar Fikrat3

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Abstract

The present study was conducted on seventy five healthy males of Swiss albino mice, which were divided into 5 groups (N=15 mice per each group). The first group were intact (control); the second one were castrated; the third group were castrated treated with 50µg/kg testosterone; the forth one were castrated treated with 10µl/g. grape juice, and the fifth one were intact treated with 3mg/kg F. hormonis.

The frozen sections of mice liver tissue from both castrated and intact treated subjects with 3mg/kg Ferula hormonis showed a strong affinity to sudanophilia (+++) as compared with the intact (control) group. Whereas frozen sections from castrated subjects treated with 50µg/kg of testosterone or with10µl/g of grape juice showed a moderate affinity to sudanophilia (++) as compared with the control. The histological sections of liver tissue from castrated group or intact treated with 3mk/kg F. hormonis revealed a decrease in glycogen contents as compared with the control group. On the other hand, sections from castrated subjects treated with 50µg/kg of testosterone or with 10µl/g of grape juice appeared normal appearance to intact (control) subjects.

Keywords

sudanophilia, liver, lipids, glycogen, ferula hormonis, castrated subjects normal appearance grape juice non-parenchymal cells abdominal obesity castration metabolic disorders hepatic steatosis

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