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Molar pregnancy – case presentation of 23-year old pregnant women with partial molar pregnancy

MOJ Anatomy & Physiology
Kovachev E,1,2 Ingilizova G,3 Anzhel S,1,2,4 Yaneva G,1 Nenkova G4

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Molar pregnancy occurs 1-2 per 1000 pregnancies, resulting in improper fertilization. Partial mole is a result of fertilization of a haploid normal oocyte with two spermatozoa simultaneously, with the formation of a zygote with a triploid set of chromosomes. Only in around 25% of cases is a variant with euploid fetus (46XX/XY). Several factors determine the prognosis of the fetus in partial molar pregnancy, such as karyotype of the fetus, size of the area with hydropic degeneration of the placenta, rate of hydropic degeneration and manifestation of fetal anemia or other obstetric complications such as preeclampsia, thyrotoxicosis and vaginal bleeding. The authors present a clinical case of partial molar pregnancy with death fetus and classical clinical picture of the pregnant women with excessive hCG values, teca lutein cysts and vaginal bleeding. The available modalities for treatment are discussed, focused on vacuum curettage as the treatment of choice with lesser risk of complications and impact on the future fertility.


molar pregnancy, ultrasound findings, prognosis, treatment, hydropic degeneration, pathogenetically, proliferation, trophoblastic, undiagnosed, normal placenta, live birth, incomplete mole, healthy fetus, evacuation, medical grounds, uterine cavity, oxytocin, intramuscular application, prostaglandins