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Coronary heart disease and lipids in women  


Journal of Cardiology & Current Research
José Mendes Aldrighi,1 Anita LR Saldanha,1 Ana Paula Pantoja Margeotto,1  André Luis Valera Gasparoto,2 Tania Leme da Rocha Martinez1

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Abstract

Heart conditions in women are many times disregarded or interpreted as psychological symptoms. In this article we present the data of the high frequency of coronary heart disease as a growing concern in treating women. Coronary ischemic diseases raise a question among epidemiologists regarding menopause being an additional risk factor for ischemic heart disease, since age over 55years in women (age at which women on average have already experienced menopause) and over 45years in men are independent risk factors. It is understood by menopause the deprivation of protective estrogens against atherosclerosis. It is known that atherosclerosis begins in childhood and will usually manifest after 55years in men and 65years in women. Old age is a marker of the amount of established atherosclerotic plaques. The higher the amount of plaques, the higher the risk of ischemic heart disease. Prospective studies with hormone replacement therapy in women without atherosclerosis may clarify the role of estrogen deprivation in atherogenesis.

Keywords

women, heart, lipids, hormones, risk factors, AMI, acute myocardial infarction, Apo A-I - Apoprotein A-I, Apo B, apolipoprotein B, CAD, coronary artery disease, CVD, cardiovascular disease, HDL-c, high density lipoprotein cholesterol, VLDL, very low density lipoprotein

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