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Anti-diabetic, haematinic and anti-cholesterolmic effects of carrot (Daucus carota Linn.) juice metabolites to cure alloxan monohydrate induced type-1 diabetes in albino rats

Journal of Diabetes, Metabolic Disorders & Control
Sanjeev Kumar,1 Kumari Shachi,2 Nayan Kumar Prasad,3 NK Dubey,4 Usha Dubey5

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Introduction: In present study an effort has been made to assess the hypoglycemic, Anticholestrolemic and haematinic activity of carrot juice in alloxan monohydrate induced experimental animal model.
Materials and methods: Rats were acclimatized for 7 days in lab temperature. All animals were given standard water and pellet diet. Diabetes was induced in rats with the help of alloxan monohydrate (140mg/kg body weight). After alloxan monohydrate injection rats were separated and treatment started with carrot juice and insulin.
Results and discussion: A marked rise in fasting blood glucose as well as serum cholesterol level was observed in diabetic control rats when compared to normal control rats. Antihyperglycemic, Anti-cholesterolmic and haematinic activity observed in carrot juice administered rats on 7th,14th,21st and 28th days post treatment. Anti-hyperglycemic and anti-cholesterol mic activity was found less effective than that of insulin treatment group.
Conclusion: It is hope that present investigation will be helpful in establishing a scientific basis for antidiabetic, haematinic and Anti-cholesterolmic effects in experimental animal model. The results are (<0.001) statistically significant.


daucus carota, diabetes, blood glucose, insulin, anti-cholesterolmic