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Clinical relevance of endometrial polyps diagnosed by hysteroscopy in 613 infertile women: a retrospective, single-center, cohort study

Obstetrics & Gynecology International Journal
Hiroki Onoue, Tsukasa Baba, Kanako Koiwa, Michiko Kon, Maki Ikeda, Jin Kumagai


Purpose: This study aimed to reveal the clinical significance of hysteroscopyin infertility treatment.
Methods: This retrospective, single-center, cohort study included 613 women of reproductive age who underwent hysteroscopy between April 2011 and March 2016. All women underwent a routine infertility work-up including transvaginal sonography, hysterosalpingography, and blood tests, and analysis of their husband’s semen was performed. The Student t, Mann-Whitney, and Fisher exact tests were used to analyze the data.
Results: Hysteroscopy as a routine work-up revealed an abnormal uterine cavity in 141 women (22.1%) and 114 endometrial polyps (80.9%). Endometrial polyps were more frequently observed in those with primary infertility (p<.005) and endometriosis (p<.005) than those without these conditions. Endometrial polyps were rarely observed in those with recurrent pregnancy loss (p<.05).
Conclusion: Hysteroscopy is recommended as a routine work-up before fertility treatment given the prevalence of endometrial polyps, especially for women with endometrioma, and their impacts on embryo implantation failure.


Endometrial polyps, Hysteroscopy, Infertile women, Gynecological procedure