A case of dubin johnson syndrome in twin pregnancy
- International Journal of Pregnancy & Child Birth
Ibarguengoitia-Ochoa Francisco,1 Davila-Bricio José Luis,1 Ruiz-Beltrán Maximiliano,2 Sepúlveda-Rivera Cintia María1
Background: Dubin Johnson syndrome is a variety of inherited hyperbilirubinemia and is recognized by a low elevation of conjugated bilirubin without other signs of liver damage.Objective: To present perinatal results of a patient diagnosed with Dubin Johnson syndrome.
Methods: The clinical file of a patient diagnosed with Dubin Johnson syndrome during pregnancy, treated at the Instituto Nacional de Perinatología was reviewed.
Results: 34-year-old patient with no history of fever, pruritus, malaise or abdominal pain; Due to the macroscopic characteristics of the liver during a laparoscopic cholecystectomy at 23 years of age, a biopsy was taken which confirmed the diagnosis of Dubin-Johnson syndrome. She began prenatal control at 17 weeks gestation. Serial bilirubin determinations ranged between 3.4 and 4.5 mg / dl. Intrauterine growth restriction was presented in one of the fetuses.
Conclusion: Dubin Johnson syndrome is a benign condition, the disease must be differentiated from other conditions that present hyperbilirubinemia specifically in pregnancy in order to stratify management
pregnancy, dubin johnson, syndrome, bilirubin, intra-hepatic cholestasis, acute fatty liver